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Safarina Golfiani Malik

Head of Laboratory

Qualification:

  • PhD (Monash University, Australia)
  • MSc (University of Indonesia, Indonesia)
  • DVM (Bogor Agricultural Institute, Indonesia)

Safarina (Ina) currently serves as Principal Secretary of Eijkman Institute and head of Genome Diversity and Diseases Laboratory. She is the principal investigator for mitochondria and lifestyle diseases research activities. Ina supervises wide range of projects, including malaria in pregnancy, gut microbes studies, and association study of genetic diversity and diseases. 

Ina is actively reviewing research proposal for Risbin Iptekdok and Indonesian Danone Institute. She also has a long list of experience in reviewing journal, including BMC Research Notes, Cardiovascular Diabetology, and International Journal of Medicine and Medical Sciences. 

Ina is member of Eijkman Institute Research Ethics Commission and Faculty of Medicine University of Indonesia Research Ethics Commitee. She is also scientific member of Indonesian Danone Institute. 


Contact: ina@eijkman.go.id

Interests:

  • Molecular pathology of inherited disorders of the energy-transducing membrane
  • Mitochondrial genetics and dysfunction associated with complex and polygenic diseases
  • Human niche construction
  • Genetic diversity, gut microbes and lifestyle diseases
  • Mechanism of bilirubin toxicity on mitochondrial functions, and bilirubin toxicity in neonates
  • Fetal programming of impaired nutrition: role of malaria infection in pregnancy
  • Maternal genetic factors and response to supplementation during pregnancy.

Awards:

  • Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Fellowship to attend the 7th Congress on Advances in Biochemistry and Molecular Biology, Sydney, Australia (24-29 September 1995)
  • International Genetic Federation (IGF) Travel Bursaries to attend the XIX International Congress of Genetics, Melbourne, Australia (6-11 July 2003)
  • International Mobility Project Fellowship 2006 from AREA Science Park, Trieste, Italy (8 August-4 September 2006)
  • TWAS Research Grant (2006)
  • Visiting Scientist Fellowship 2010 from Centro Studi Fegato, Trieste, Italy (12 February-12 March 2010)
  • Women Reach Initiative 2013 from Harvard School of Public Health (2013)

Publications

  1. Prevalence and epidemiological characteristics of COVID-19 after one year of pandemic in Jakarta and neighbouring areas, Indonesia: A single center study.
    PLoS One. 2022 May 12;17(5):e0268241. doi: 10.1371/journal.pone.0268241. eCollection 2022.
    PubMed
  2. Whole-Genome Sequencing of SARS-CoV-2 Infection in a Cluster of Immunocompromised Children in Indonesia.
    Front Med (Lausanne). 2022 Mar 4;9:835998. doi: 10.3389/fmed.2022.835998. eCollection 2022.
    PubMed
  3. COVID-19 prevalence among healthcare workers in Jakarta and neighbouring areas in Indonesia during early 2020 pandemic.
    Ann Med. 2021 Dec;53(1):1896-1904. doi: 10.1080/07853890.2021.1975309.
    PubMed
  4. Characteristics of children with confirmed SARS-CoV-2 infection in Indonesia.
    J Clin Virol Plus. 2021 Sep;1(3):100027. doi: 10.1016/j.jcvp.2021.100027. Epub 2021 Jun 11.
    PubMed
  5. The Association of Maternal Vitamin D Status during Pregnancy and Neonatal Anthropometric Measurements: A Longitudinal Study in Minangkabau Pregnant Women, Indonesia.
    J Nutr Sci Vitaminol (Tokyo). 2020;66(Supplement):S63-S70. doi: 10.3177/jnsv.66.S63.
    PubMed
  6. The Association between Vitamin D-Related Gene Polymorphisms and Serum 25-Hydroxyvitamin D Concentration: A Prospective Cohort Study in Pregnant Minangkabau Women, Indonesia.
    J Nutr Sci Vitaminol (Tokyo). 2020;66(Supplement):S295-S303. doi: 10.3177/jnsv.66.S295.
    PubMed
  7. Non-nutritional anemia: Malaria, thalassemia, G6PD deficiency and tuberculosis in Indonesia.
    Asia Pac J Clin Nutr. 2020;29(Suppl 1):S32-S40. doi: 10.6133/apjcn.202012_29(S1).04.
    PubMed
  8. Maternal biomarker patterns for metabolism and inflammation in pregnancy are influenced by multiple micronutrient supplementation and associated with child biomarker patterns and nutritional status at 9-12 years of age.
    PLoS One. 2020 Aug 7;15(8):e0216848. doi: 10.1371/journal.pone.0216848. eCollection 2020.
    PubMed
  9. A genetic approach to study the relationship between maternal Vitamin D status and newborn anthropometry measurements: the Vitamin D pregnant mother (VDPM) cohort study.
    J Diabetes Metab Disord. 2020 Jan 27;19(1):91-103. doi: 10.1007/s40200-019-00480-5. eCollection 2020 Jun.
    PubMed
  10. Obesity in the Balinese is associated with FTO rs9939609 and rs1421085 single nucleotide polymorphisms.
    PeerJ. 2020 Jan 3;8:e8327. doi: 10.7717/peerj.8327. eCollection 2020.
    PubMed
  11. Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales.
    R Soc Open Sci. 2019 Aug 28;6(8):190733. doi: 10.1098/rsos.190733. eCollection 2019 Aug.
    PubMed
  12. Vitamin D deficiency status and its related risk factors during early pregnancy: a cross-sectional study of pregnant Minangkabau women, Indonesia.
    BMC Pregnancy Childbirth. 2019 May 22;19(1):183. doi: 10.1186/s12884-019-2341-4.
    PubMed
  13. Obesity risk and preference for high dietary fat intake are determined by FTO rs9939609 gene polymorphism in selected Indonesian adults.
    Asia Pac J Clin Nutr. 2019;28(1):183-191. doi: 10.6133/apjcn.201903_28(1).0024.
    PubMed
  14. Placental mitochondrial DNA copy number is associated with reduced birth weight in women with placental malaria.
    Placenta. 2019 May;80:1-3. doi: 10.1016/j.placenta.2019.03.005. Epub 2019 Mar 15.
    PubMed
  15. Polymorphisms of Aldose Reductase (ALR2) Regulatory Gene are Risk Factors for Diabetic Retinopathy in Type-2 Diabetes Mellitus Patients in Bali, Indonesia.
    Open Ophthalmol J. 2018 Oct 18;12:281-288. doi: 10.2174/1874364101812010281. eCollection 2018.
    PubMed
  16. Increased mitochondrial DNA copy number in maternal peripheral blood is associated with low birth weight in Lombok, Indonesia.
    Placenta. 2018 Oct;70:1-3. doi: 10.1016/j.placenta.2018.08.001. Epub 2018 Aug 9.
    PubMed
  17. Placental weight ratio affects placental mRNA expression of insulin-like growth factor-I and long isoform of the leptin receptor in Plasmodium falciparuminfected pregnant women.
    Asia Pac J Clin Nutr. 2016 Dec;25(Suppl 1):S75-S82.
    PubMed
  18. From 'lactose intolerance' to 'lactose nutrition'.

    PubMed
  19. Uncoupling protein 2 gene polymorphisms are associated with obesity.
    Cardiovasc Diabetol. 2012 Apr 25;11:41. doi: 10.1186/1475-2840-11-41.
    PubMed
  20. Association of beta3-adrenergic receptor (ADRB3) Trp64Arg gene polymorphism with obesity and metabolic syndrome in the Balinese: a pilot study.
    BMC Res Notes. 2011 May 27;4:167. doi: 10.1186/1756-0500-4-167.
    PubMed