Rintis Noviyanti

Senior Research Fellow

Qualification:

  • B.Sc(Hons) (University of Indonesia)
  • Postgraduate Diploma (University of Melbourne)
  • Ph.D (University of Melbourne)

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Publications

  • Plasmodium falciparum and Plasmodium vivax Demonstrate Contrasting Chloroquine Resistance Reversal Phenotypes. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00355-17. doi: 10.1128/AAC.00355-17. Print 2017 Aug.
  • Genetic micro-epidemiology of malaria in Papua Indonesia: Extensive P. vivax diversity and a distinct subpopulation of asymptomatic P. falciparum infections. PLoS One. 2017 May 12;12(5):e0177445. doi: 10.1371/journal.pone.0177445. eCollection 2017.
  • VivaxGEN: An open access platform for comparative analysis of short tandem repeat genotyping data in Plasmodium vivax populations. PLoS Negl Trop Dis. 2017 Mar 31;11(3):e0005465. doi: 10.1371/journal.pntd.0005465. eCollection 2017 Mar.
  • Submicroscopic and Asymptomatic Plasmodium Parasitaemia Associated with Significant Risk of Anaemia in Papua, Indonesia. PLoS One. 2016 Oct 27;11(10):e0165340. doi: 10.1371/journal.pone.0165340. eCollection 2016.
  • A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria. ACS Infect Dis. 2016 Dec 9;2(12):945-957. Epub 2016 Oct 4.
  • Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling. PLoS Med. 2016 Oct 4;13(10):e1002138. doi: 10.1371/journal.pmed.1002138. eCollection 2016 Oct.
  • Genomic analysis of local variation and recent evolution in Plasmodium vivax. Nat Genet. 2016 Aug;48(8):959-64. doi: 10.1038/ng.3599. Epub 2016 Jun 27.
  • Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub-microscopic Plasmodium falciparum or Plasmodium vivax infection. Malar J. 2016 Jun 21;15:328. doi: 10.1186/s12936-016-1382-7.
  • Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria. Malar J. 2016 May 5;15(1):258. doi: 10.1186/s12936-016-1296-4.
  • Analysis of ex vivo drug response data of Plasmodium clinical isolates: the pros and cons of different computer programs and online platforms. Malar J. 2016 Mar 2;15(1):137. doi: 10.1186/s12936-016-1173-1.
  • Randomized trial of primaquine hypnozoitocidal efficacy when administered with artemisinin-combined blood schizontocides for radical cure of Plasmodium vivax in Indonesia. BMC Med. 2015 Dec 11;13(1):294. doi: 10.1186/s12916-015-0535-9.
  • Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility. Antimicrob Agents Chemother. 2015 Nov 2;60(1):361-7. doi: 10.1128/AAC.02207-15.
  • Quantification of Plasmodium ex vivo drug susceptibility by flow cytometry. Malar J. 2015 Oct 24;14(1):417. doi: 10.1186/s12936-015-0940-8.
  • Potent Ex Vivo Activity of Naphthoquine and Methylene Blue against Drug-Resistant Clinical Isolates of Plasmodium falciparum and Plasmodium vivax. Antimicrob Agents Chemother. 2015 Oct;59(10):6117-24. doi: 10.1128/AAC.00874-15. Epub 2015 Jul 20.
  • Contrasting ex vivo efficacies of "reversed chloroquine" compounds in chloroquine-resistant Plasmodium falciparum and P. vivax isolates. Antimicrob Agents Chemother. 2015 Sep;59(9):5721-6. doi: 10.1128/AAC.01048-15. Epub 2015 Jul 6.
  • A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature. 2015 Jun 18;522(7556):315-20. doi: 10.1038/nature14451.
  • Preserved dendritic cell HLA-DR expression and reduced regulatory T cell activation in asymptomatic Plasmodium falciparum and P. vivax infection. Infect Immun. 2015 Jun 1. pii: IAI.00226-15.
  • Contrasting Transmission Dynamics of Co-endemic Plasmodium vivax and P. falciparum: Implications for Malaria Control and Elimination. PLoS Negl Trop Dis. 2015 May 7;9(5):e0003739. doi: 10.1371/journal.pntd.0003739. eCollection 2015 May.
  • G6PD Deficiency at Sumba in Eastern Indonesia Is Prevalent, Diverse and Severe: Implications for Primaquine Therapy against Relapsing Vivax Malaria. PLoS Negl Trop Dis. 2015 Mar 6;9(3):e0003602. doi: 10.1371/journal.pntd.0003602. eCollection 2015 Mar.
  • The clinical and public health problem of relapse despite primaquine therapy: case review of repeated relapses of Plasmodium vivax acquired in Papua New Guinea. Malar J. 2014 Dec 12;13(1):488. doi: 10.1186/1475-2875-13-488.
  • Platelet activation determines angiopoietin-1 and VEGF levels in malaria: implications for their use as biomarkers. PLoS One. 2013 Jun 3;8(6):e64850. doi: 10.1371/journal.pone.0064850. Print 2014.
  • Quinolone-3-diarylethers: a new class of antimalarial drug. Sci Transl Med. 2013 Mar 20;5(177):177ra37. doi: 10.1126/scitranslmed.3005029.
  • Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing. PLoS One. 2013;8(1):e53160. doi: 10.1371/journal.pone.0053160. Epub 2013 Jan 4.
  • Transcribed var genes associated with placental malaria in Malawian women. Infect Immun. 2006 Aug;74(8):4875-83.
  • Malaria in Wanokaka and Loli sub-districts, West Sumba District, East Nusa Tenggara Province, Indonesia. Am J Trop Med Hyg. 2006 May;74(5):733-7.
  • Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype. Mol Microbiol. 2005 May;56(3):774-88.
  • Phenotypic switching and var gene transcription in Plasmodium falciparum. Adv Exp Med Biol. 2003;531:149-59.
  • Transcription of multiple var genes by individual, trophozoite-stage Plasmodium falciparum cells expressing a chondroitin sulphate A binding phenotype. Mol Microbiol. 2002 Mar;43(5):1285-93.
  • Multiple var gene transcripts are expressed in Plasmodium falciparum infected erythrocytes selected for adhesion. Mol Biochem Parasitol. 2001 May;114(2):227-37.