Meta Dewi Thedja

Senior Research Fellow


  • PhD. [Utrecht University, The Netherlands]
  • M.Biomed. [University of Indonesia, Indonesia]
  • M.D. [Tarumanagara University, Indonesia]

Meta is a senior research fellow at the Eijkman Institute for Molecular Biology since 2000. She was involved in the study of viral hepatitis, mainly hepatitis B, which is prevalent in our region. Meta has succeeded in her PhD-defense at the University Medical Center (UMC) Utrecht, Netherlands that was held on 19 October 2012, with a study focusing on the genetic diversity of hepatitis B in Indonesia. Her study was a collaboration study between the Eijkman Institute Jakarta and the Eijkman-Winkler Institute UMC Utrecht.



Ie SI, Turyadi, Sidarta E, Sadhewa A, Purnomo GA, Soedarmono YSM, Pattiiha MZ, Thedja MD, Harahap AR, Muljono DH. High prevalence of hepatitis B virus (HBV) infection in young adults in Ternate, Eastern Indonesia. Am J Trop Med Hyg (Submitted 5 Mei 2015).

Thedja MD, Muljono DH, Ie SI, Sidarta E, Turyadi, Verhoef J, Marzuki S. Genogeography and immune epitope characteristics of hepatitis B virus genotype C reveals two distinct types: Asian and Papua-Pacific. PLoS One 2015 (Accepted).

Darmawan E, Turyadi, El Khobar KE, Nursanty NKD, Thedja MD, Muljono DH. Occult hepatitis B in young adults in Banjarmasin, South Kalimantan, Indonesia. J Med Virol, 2015 Feb; 87(2); 199-207; DOI: 10.1002/jmv.24045.

Turyadi, Thedja MD, Ie SI, Harahap AR, El-Khobar KE, Roni M, Muljono DH. HBsAg, HBeAg and HBV DNA level changes and precore/basal core promoter mutations in the natural history of chronic hepatitis B in Indonesian patients. Hepatol Int 2013; 7:969-80; DOI 10.1007/s12072-013-9438-z.

Thedja MD, Muljono DH, Nurainy N, Sukowati CH, Verhoef J, Marzuki S. Ethnogeographical structure of hepatitis B virus genotype distribution in Indonesia. Arch Virol 2011; 156:855-68; DOI: 10.1007/s00705-011-0926-y.

Ie SI, Thedja MD, Roni M, Muljono DH. Prediction of Conformational Changes by Single Mutation in the Hepatitis B Virus Surface Antigen (HBsAg) Identified in HBsAg-Negative Blood Donors. Virol J. 2010; 7: 326.

Thedja MD, Roni M, Harahap AR, Siregar NC, Ie SI, Muljono DH. Occult hepatitis B in blood donors in Indonesia: altered antigenicity of the hepatitis B virus surface protein. Hepatol Int 2010; 4: 608–14; DOI: 10.1007/s12072-010-9203-5.


  1. High Prevalence of Hepatitis B Virus Infection in Young Adults in Ternate, Eastern Indonesia.
    Am J Trop Med Hyg. 2015 Dec 9;93(6):1349-55. doi: 10.4269/ajtmh.15-0331. Epub 2015 Sep 21.