Infectious Disease Research

Research topics related to infectious diseases are:

Malaria

  • Molecular mechanisms underlying Plasmodium resistance to antimalarial drugs
  • Molecular mechanisms underlying mosquito resistances to insecticides
  • Molecular taxonomy of anopheles mosquitoes
  • Antimalarial drug discovery through natural products
  • Molecular pathogenesis of malaria infection, including severe malaria and malaria in pregnancy
  • Research towards malaria vaccine development
  • Understanding the development of immunity to malaria parasites
  • In vitro and molecular studies of malaria parasites
  • Invasion of malaria parasites into human erythrocytes
  • Molecular genotyping of malaria parasites using microsatellites and whole genome sequencing
  • Genome-wide association study of Plasmodium vivax drug resistancy

Hepatitis

  • Serological and molecular epidemiology of hepatitis B virus (HBV) in Indonesia
  • Mother-to-child (vertical) transmission of HBV
  • Serological and molecular epidemiology of hepatitis C virus (HCV) in Indonesia
  • Occult hepatitis B in blood donors in Indonesia
  • Occult hepatitis B in healthy population in Indonesia
  • The role of preS2 genetic variation in chronic hepatitis B patients, cirrhotic hepatic, and hepatocellular carcinoma
  • Characterization of X, core promoter, and precore genes of hepatitis B virus in chronic hepatitis B patients in Indonesia
  • Molecular background of occult hepatitis B in Indonesia
  • Molecular protein modeling of variation/mutation in HBV surface and polymerase genes
  • Immunoinformatics study of HBV surface and core proteins
  • Development and production of hepatitis B recombinant vaccine

Dengue

  • Molecular epidemiology of dengue in Indonesia
  • Genetics and biological characteristics of dengue virus in Indonesia
  • Host response against dengue infection
  • Dengue vaccine clinical trial