Bioinformatics Laboratory

Bioinformatics Laboratory's major role is to support the bioinformatics and data analysis for all research groups within the Eijkman Institute. The laboratory is also given the task of managing the IT and computing infrastructure for the institute.

The laboratory supports the bioinformatics and data analysis at the institute by:

  • performing bioinformatics and data analysis for all research groups that require sound analysis and interpretation of their empirical/experimental data,
  • providing the necessary bioinformatics and statistical means and tools to support the analysis, and
  • training institute's staff and students in bioinformatics and data analysis

The laboratory is mainly conducting activities in:

  • empirical/experimental data management
  • biostatistical analysis
  • genome analysis
  • evolution study
  • genetic association study
  • protein modelling and molecular dynamics

People

Publication

  • Genomic characterization of Zika virus isolated from Indonesia. Virology. 2017 Jul 26;510:248-251. doi: 10.1016/j.virol.2017.07.026.
  • Genomic landscape of human diversity across Madagascar. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6498-E6506. doi: 10.1073/pnas.1704906114. Epub 2017 Jul 17.
  • Clinical and virological characteristics of dengue in Surabaya, Indonesia. PLoS One. 2017 Jun 2;12(6):e0178443. doi: 10.1371/journal.pone.0178443. eCollection 2017.
  • The last sea nomads of the Indonesian archipelago: genomic origins and dispersal. Eur J Hum Genet. 2017 Aug;25(8):1004-1010. doi: 10.1038/ejhg.2017.88. Epub 2017 May 17.
  • VivaxGEN: An open access platform for comparative analysis of short tandem repeat genotyping data in Plasmodium vivax populations. PLoS Negl Trop Dis. 2017 Mar 31;11(3):e0005465. doi: 10.1371/journal.pntd.0005465. eCollection 2017 Mar.
  • Genomic analysis and growth characteristic of dengue viruses from Makassar, Indonesia. Infect Genet Evol. 2015 Mar 14. pii: S1567-1348(15)00090-8. doi: 10.1016/j.meegid.2015.03.006.
  • Performance of Simplexa dengue molecular assay compared to conventional and SYBR green RT-PCR for detection of dengue infection in Indonesia. PLoS One. 2014 Aug 7;9(8):e103815. doi: 10.1371/journal.pone.0103815. eCollection 2014.
  • Genetic diversity and population structure of Plasmodium vivax in Central China. Malar J. 2014 Jul 9;13:262. doi: 10.1186/1475-2875-13-262.
  • Molecular surveillance of Dengue in Sukabumi, West Java province, Indonesia. J Infect Dev Ctries. 2014 Jun 11;8(6):733-41. doi: 10.3855/jidc.3959.
  • Performance of commercial dengue NS1 ELISA and molecular analysis of NS1 gene of dengue viruses obtained during surveillance in Indonesia. BMC Infect Dis. 2013 Dec 29;13:611. doi: 10.1186/1471-2334-13-611.
  • Molecular surveillance of dengue in Semarang, Indonesia revealed the circulation of an old genotype of dengue virus serotype-1. PLoS Negl Trop Dis. 2013 Aug 8;7(8):e2354. doi: 10.1371/journal.pntd.0002354. eCollection 2013.
  • The baseline distribution of malaria in the initial phase of elimination in Sabang Municipality, Aceh Province, Indonesia. Malar J. 2012 Aug 21;11:291. doi: 10.1186/1475-2875-11-291.
  • Uncoupling protein 2 gene polymorphisms are associated with obesity. Cardiovasc Diabetol. 2012 Apr 25;11:41. doi: 10.1186/1475-2840-11-41.
  • Existence of the rdl mutant alleles among the anopheles malaria vector in Indonesia. Malar J. 2012 Feb 25;11:57. doi: 10.1186/1475-2875-11-57.
  • Association of beta3-adrenergic receptor (ADRB3) Trp64Arg gene polymorphism with obesity and metabolic syndrome in the Balinese: a pilot study. BMC Res Notes. 2011 May 27;4:167. doi: 10.1186/1756-0500-4-167.
  • Seasonal distribution of anti-malarial drug resistance alleles on the island of Sumba, Indonesia. Malar J. 2009 Sep 29;8:222. doi: 10.1186/1475-2875-8-222.
  • Seasonal prevalence of malaria in West Sumba district, Indonesia. Malar J. 2009 Jan 9;8:8. doi: 10.1186/1475-2875-8-8.

Activities/Topics/Projects