Eijkman Oxford Clinical Research Unit (EOCRU)
EOCRU was established in 2008 by a memorandum of understanding between the Eijkman Institute for Molecular Biology (EIMB) and the University of Oxford, as an embedded unit of the EIMB. These institutions now collaborate in clinical, laboratory, and field research on infectious diseases of public health importance in Indonesia. EOCRU is directed by Prof J. Kevin Baird and comprises three research groups and five supporting service groups.
The Eijkman-Oxford Clinical Research Unit (EOCRU), with its Indonesian hosts and partners, aims to collaboratively develop and pursue a research agenda of relevance to Indonesian healthcare providers and their patients. We are especially committed to infectious diseases that impose burdens of preventable or treatable morbidity and mortality in Southeast Asia, including tuberculosis, malaria, and other emerging and neglected infections. EOCRU’s vision is to compose an important and highly active centre of biomedical research excellence, with our hosts and partners, focusing on opportunities to improve the prevention, diagnosis, and treatment of these endemic infections by conducting robust randomized clinical trials that may directly impact practice and improve the health outcomes in Indonesia and the region.
Field-base team
Unit structure
Head Unit : Prof. J. Kevin Baird
Research Group:
- Malaria Program (Prof. J. Kevin Baird)
- Spatial Epidemiology Program (Iqbal RF Elyazar)
- Clinical Epidemiology (Anuraj Shankar)
- Clinical infectious Disease Program
- Finance and Admin
- Secretary to Head Unit:I.D.A.Y.R. Chrisverani
- Finance Manager : Agus
- Operations Manager : Rizky Baihaqi Halim
- Clinical Research Operations Manager: Mutia Rahardjani
- Finance Staff : Sisca Karo Karo, Eni Nawastuti
- Secretary/Admin Assistant : Andrina S. Rivai
- Finance/Admin Assistant: Dian Surtiningsih
- Laboratory Support
- Clinical Medicine
- IOCRL - FKUI
- Statistics and Data Management
- Regulatory and Governance
- Logistic and IT
- Public Engagement Officer
People
- Andrianto, Adhi (Data management and IT support)
- Agus, (Finance Manager)
- Baird, John Kevin (Head of Eijkman Oxford Clinical Research Unit)
- Basri, Hasan (Senior Clinical Research Associate)
- Cahyaningati, Syavira (Laboratory Technician)
- Chand, Krisin (Field-site Clinical and Microscopic Manager )
- Chrisverani, I.D.A.Y.R. (Administrative Assistant to EOCRU Head of Unit)
- Dewi, Mewahyu (Senior Research Assistant)
- Dien, Soraya Weldina Ragil (Public Engagement Officer)
- Djaafara, Bimandra Adiputra (Statistician, PhD Student)
- Ekawati, Lenny L. (PhD Student)
- Elyazar, Iqbal RF (Deputy Head Unit and Biostatistician)
- Hutahaean, Gladis Roito (Study physician)
- Halim, Rizky Baihaqi (Operations Manager)
- Hamers, Raph (Senior Clinician Scientist)
- Handayani, Winahyu (Site Clinical Trial Data Entry)
- Jaya, Ungke Anton (Senior Virology Laboratory Analyst)
- Jeny, (Research Assistant)
- Kalbuadi, Ichsan (Laboratory Technician)
- Karo Karo, Sisca (Admin & Finance Assistant)
- Kosasih, Ayleen Alicia (Research Staff and PhD student)
- Lestari, Karina Dian (Data Analyst)
- Limato, Ralalicia (Study coordinator and PhD student)
- Lina, Rosa Nora (Study Coordinator)
- Machpud, Nunung Nuraini (Epidemiologist)
- Christian, Michael (Study physician/Health and safety officer)
- Nawastuti, Eni (Finance Staff)
- Prastio, Ariyanto (Laboratory Technician)
- Pratama, AA Raka (Laboratory support and malaria microscopist)
- Rahardjani, Mutia (Clinical Research Operations Manager)
- Rivai, Andrina S. (Administrative Assistant)
- Santy, Yulia Widya (Site Laboratory Manager)
- Saraswati, Kartika (PhD Student)
- Soebianto, Saraswati ( Immunology and Molecular Diagnostic Laboratory Scientist)
- Subekti, Decy (Research scientist/manager of clinical microbiology laboratory)
- Sudiana, Dedi (IT & Logistics Officer)
- Sunardi, (Microscopist)
- Surendra, Henry (Epidemiologist)
- Surtiningsih, Dian (Finance and admin assistant)
- Susilowati, Novi Dwi (Laboratory Technician)
- Sutisna, Asep (Specimen Archivist and Data Entry)
- Suwarti, (Research staff)
- Vernandes, Mario (Junior Scientist For LCMSMS)
- Wardhani, Anna Laksmi Sri (Clinical Trial Coordinator)
- Waslia, Lia (Senior Research Assistant)
- Wulandari, Fitria ( Research and Grant Administrator)
- Wulandari, Ratna (Laboratory Analyst)
Publication
- Case Report: A Case of Primaquine-Induced Hemoglobinuria in Glucose-6-Phosphate Dehydrogenase-Deficient Malaria Patient in Southeastern Bangladesh.
Am J Trop Med Hyg. 2019 Nov 4. doi: 10.4269/ajtmh.19-0643.
PubMed
Activities/Topics/Projects
- A double-blind, double-dummy, randomized, parallel group, placebo-controlled, superiority study to evaluate the efficacy and safety of tafenoquine (SB-252263, WR238605) co-administered with dihydroartemisinin-piperaquine (DHA-PQP) for the radical cure of Plasmodium vivax malaria (INSPECTOR)
- A randomised double blind placebo controlled trial of adjunctive dexamethasone for the treatment of HIV-infected adults with tuberculous meningitis (ACT HIV) Short title: Adjunctive Corticosteroids for Tuberculous meningitis in HIV-infected adults (The ACT HIV trial)
- Epidemiology of G6PDd and evaluation of diagnostic technologies
- Impact of cytochrome-P450 polymorphisms on the metabolism and efficacy of primaquine and tafenoquine in anti-relapse therapy
- Improving the radical cure of Plasmodium vivax malaria: a multicenter randomized comparison of short and long course primaquine regimens (IMPROV)
- Mapping burdens of malaria in Indonesia
- Safety, tolerability, immunogenicity and protective efficacy against naturally-transmitted malaria in eastern Indonesia of two Plasmodium falciparum Sporozoite Vaccines, Sanaria® PfSPZ Vaccine and Sanaria® PfSPZ-CVac: a randomized, double-blind, placebo-controlled phase 2 trial in health Indonesian adults
- Serological markers of recent exposure as surrogate biomarkers of hypnozoite carriage: a proof-of-concept study in Indonesian soldiers