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Emerging Virus Research Unit

Emerging Virus Research Unit (EVRU) is the newly established Virology Unit at Eijkman Institute focusing on studies of endemic and emerging viruses circulating in the Indonesian Archipelago. Inaugurated in 2012, it is supported by the Indonesian Government, US-CDC, and USAID. 

Main aims of the unit:

  • To do research and to provide data on prevalence of new and emerging viruses (etiology of disease) specifically those with pandemic risk in the Indonesian Archipelago.
  • To develop and improve diagnostic capabilities for emerging viruses.

EVRU is a laboratory level 2 unit as well as tissue culture lab. In addition, a BSL-3 laboratory, serology testing laboratory space, real-time PCR, and sequencing facilities are available on site. With deep sequencing and gold standard reference assays on site, EVRU remains a unique facility to lead the way in emerging pathogen research, training and supporting public health in Indonesia.

EVRU collaborates with local partners and providing training to Indonesian scientists, veterinarians, and clinicians in conducting field, laboratory, and clinical research of pathogens that wish to implement Indonesian capacity for local diagnosis, surveillance, research, and response to emerging zoonotic infections.

People

Publication

  1. Echovirus-7 Infection in Children with Unusual Severe Manifestation: A Case Report.
    Infect Chemother. 2021 Mar;53(1):141-145. doi: 10.3947/ic.2020.0081.
    PubMed
  2. Detection of dengue virus serotype 1 in central nervous system of a child in Bandung, West Java: A case report.
    SAGE Open Med Case Rep. 2021 Jul 23;9:2050313X211034393. doi: 10.1177/2050313X211034393. eCollection 2021.
    PubMed
  3. Comparative cytokine profiling identifies common and unique serum cytokine responses in acute chikungunya and dengue virus infection.
    BMC Infect Dis. 2021 Jul 2;21(1):639. doi: 10.1186/s12879-021-06339-6.
    PubMed
  4. Convalescent plasma therapy in patients with moderate-to-severe COVID-19: A study from Indonesia for clinical research in low- and middle-income countries.
    EClinicalMedicine. 2021 Jun 4:100931. doi: 10.1016/j.eclinm.2021.100931.
    PubMed
  5. Spatiotemporal Heterogeneity of Zika Virus Transmission in Indonesia: Serosurveillance Data from a Pediatric Population.
    Am J Trop Med Hyg. 2021 May 3. pii: tpmd210010. doi: 10.4269/ajtmh.21-0010.
    PubMed
  6. An investig-ation into the epidemiology of chikungunya virus across neglected regions of Indonesia.
    PLoS Negl Trop Dis. 2020 Dec 21;14(12):e0008934. doi: 10.1371/journal.pntd.0008934. eCollection 2020 Dec.
    PubMed
  7. Molecular biology of coronaviruses: current knowledge.
    Heliyon. 2020 Aug;6(8):e04743. doi: 10.1016/j.heliyon.2020.e04743. Epub 2020 Aug 17.
    PubMed
  8. Japanese encephalitis virus infection in non-encephalitic acute febrile illness patients.
    PLoS Negl Trop Dis. 2020 Jul 14;14(7):e0008454. doi: 10.1371/journal.pntd.0008454. eCollection 2020 Jul.
    PubMed
  9. Rickettsia felis identified in two fatal cases of acute meningoencephalitis.
    PLoS Negl Trop Dis. 2020 Feb 18;14(2):e0007893. doi: 10.1371/journal.pntd.0007893.
    PubMed
  10. Absence of Evidence of Zika Virus Infection in Cord Blood and Urine from Newborns with Congenital Abnormalities, Indonesia.
    Am J Trop Med Hyg. 2020 Feb 10. doi: 10.4269/ajtmh.19-0593.
    PubMed
  11. Pathogenic viruses: Molecular detection and characterization.
    Infect Genet Evol. 2020 Jan 29:104215. doi: 10.1016/j.meegid.2020.104215.
    PubMed
  12. Detection of Multiple Viral Sequences in the Respiratory Tract Samples of Suspected MERS-CoV Patients in Jakarta, Indonesia 2015-2016.
    Int J Infect Dis. 2019 Jun 22. pii: S1201-9712(19)30267-X. doi: 10.1016/j.ijid.2019.06.022.
    PubMed
  13. Birth prevalence and characteristics of congenital cytomegalovirus infection in an urban birth cohort, Jakarta, Indonesia.
    Int J Infect Dis. 2019 Jun 14. pii: S1201-9712(19)30254-1. doi: 10.1016/j.ijid.2019.06.009.
    PubMed
  14. Detection of central nervous system viral infections in adults in Manado, North Sulawesi, Indonesia.
    PLoS One. 2018 Nov 16;13(11):e0207440. doi: 10.1371/journal.pone.0207440. eCollection 2018.
    PubMed
  15. Presentation, etiology, and outcome of brain infections in an Indonesian hospital: A cohort study.
    Neurol Clin Pract. 2018 Oct;8(5):379-388. doi: 10.1212/CPJ.0000000000000517.
    PubMed
  16. Zika Virus Seropositivity in 1-4-Year-Old Children, Indonesia, 2014.
    Emerg Infect Dis. 2018 Sep;24(9). doi: 10.3201/eid2409.180582.
    PubMed
  17. Characterization of rhinovirus C from a 4-year-old boy with acute onset dilated cardiomyopathy in Jakarta, Indonesia.
    JMM Case Rep. 2018 Feb 1;5(9):e005139. doi: 10.1099/jmmcr.0.005139. eCollection 2018 Sep.
    PubMed
  18. Isolation and complete genome analysis of neurotropic dengue virus serotype 3 from the cerebrospinal fluid of an encephalitis patient.
    PLoS Negl Trop Dis. 2018 Jan 12;12(1):e0006198. doi: 10.1371/journal.pntd.0006198.
    PubMed
  19. Chikungunya Detection during Dengue Outbreak in Sumatra, Indonesia: Clinical Manifestations and Virological Profile.
    Am J Trop Med Hyg. 2017 Sep 25. doi: 10.4269/ajtmh.16-0935.
    PubMed
  20. Genomic characterization of Zika virus isolated from Indonesia.
    Virology. 2017 Jul 26;510:248-251. doi: 10.1016/j.virol.2017.07.026.
    PubMed
  21. Chloroquine efficacy for Plasmodium vivax in Myanmar in populations with high genetic diversity and moderate parasite gene flow.
    Malar J. 2017 Jul 10;16(1):281. doi: 10.1186/s12936-017-1912-y.
    PubMed
  22. Chikungunya fever outbreak identified in North Bali, Indonesia.
    Trans R Soc Trop Med Hyg. 2017 Jul 1;111(7):325-327. doi: 10.1093/trstmh/trx054.
    PubMed
  23. Occurrence of measles genotype D8 during a 2014 outbreak in Banjarmasin, South Kalimantan, Indonesia.
    Int J Infect Dis. 2017 Jan;54:1-3. doi: 10.1016/j.ijid.2016.10.029. Epub 2016 Nov 4.
    PubMed
  24. Detection and identification of coxsackievirus B3 from sera of an Indonesian patient with undifferentiated febrile illness.
    J Infect Dev Ctries. 2016 Aug 31;10(8):880-3. doi: 10.3855/jidc.7573.
    PubMed
  25. Isolation of Zika Virus from Febrile Patient, Indonesia.
    Emerg Infect Dis. 2016 May;22(5):924-925. doi: 10.3201/eid2205.151915.
    PubMed
  26. West Nile virus documented in Indonesia from acute febrile illness specimens.
    Am J Trop Med Hyg. 2014 Feb;90(2):260-2. doi: 10.4269/ajtmh.13-0445. Epub 2014 Jan 13.
    PubMed

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